Courses

BN 1740 The Diseased Brain We are in the midst of a revolution in our understanding of neurological and psychiatric disease. A confluence of genetic, imaging, and cell biological approaches is bringing to light the underlying causes and pathology of a host of brain and nervous system disorders. The goals of this course are to illustrate what basic science can teach us about disease and how these pathologies illuminate the functioning of the normal nervous system. Consideration will be given to monoallelic diseases (e.g. Fragile X Syndrome, Duchenne Muscular Dystrophy and Tuberous Sclerosis) as well as genetically complex disorders where genome-environment interactions seem likely to contribute to the pathology – e.g. Autism and Alzheimer’s Disease). Emphasis will be on the cellular and molecular basis of these disorders and how insights at these levels might lead to the development of therapies.

Pre-requisites: BN 1020, BN 1040 and BI 0470 suggested

Neuroscience courses homepage ( http://neuroscience.brown.edu/courses.html )