PubMed-listed publications authored by Diane Lipscombe


Select publications/articles:

Allen SE, Darnell RB, Lipscombe D. (2010) The neuronal splicing factor Nova controls alternative splicing in N-type and P-type CaV2 calcium channels.
Channels Nov 1;4(6). [PubMed]


Andrade A, Denome S, Jiang YQ, Marangoudakis S, Lipscombe D. (2010) Opioid inhibition of N-type Ca2+ channels and spinal analgesia couple to alternative splicing.
Nature Neuroscience Oct;13(10):1249-56. [PubMed]


Andrade A, Sandoval A, González-Ramírez R, Lipscombe D, Campbell KP, Felix R. (2009) The alpha(2)delta subunit augments functional expression and modifies the pharmacology of Ca(V)1.3 L-type channels.
Cell Calcium Oct;46(4):282-92. [PubMed]


Jakubek LM, Marangoudakis S, Raingo J, Liu X, Lipscombe D, Hurt RH. (2009) The inhibition of neuronal calcium ion channels by trace levels of yttrium released from carbon nanotubes.
Biomaterials Oct;30(31):6351-7. [PubMed]


Lipscombe D, Pan JQ. (2009) Tripping the HCN breaker.
Neuron Jun 25;62(6):747-50. [PubMed]


Diane Lipscombe, Summer E. Allen, Annette C. Gray, Spiro Marangoudakis, and Jesica Raingo (2009) Alternative splicing of neuronal CaV2 calcium channels.
Structure, Function and Modulation of Neuronal Voltage-Gated Ion Channels Eds: Leonard K. Kaczmarek and Valentin K. Gribkoff. ISBN: 978-0-471-93013-6, 475 pages. [Wiley Publishing Group]


Lipscombe D, Jakubek LM, Marangoudakis S, Raingo J, Hurt RH. (2008) Single walled carbon nanotubes disable neuronal calcium ion channels through yttrium release.
Nature News 16 November 2008:Society for Neuroscience Poster 132.10/D35. [Nature News]


Lipscombe D, & Raingo J. (2007) Alternative Splicing Matters: N-type Calcium Channels in Nociceptors.
Channels Jul-Aug 1(4):225-7. [PubMed]


Fairbrother W, Lipscombe D. (2007) Repressing the neuron within.
Bioessays Jan;30(1):1-4. [PubMed]


Altier C, Dale CS, Kisilevsky AE, Chapman K, Castiglioni AJ, Matthews EA, Evans RM, Dickenson AH, Lipscombe D, Vergnolle N, Zamponi GW. (2007) Differential role of N-type calcium channel splice isoforms in pain.
J Neurosci. Jun 13;27(24):6363-73. [PubMed]


Gray AC, Raingo J, Lipscombe D. (2007) Neuronal calcium channels: splicing for optimal performance.
Cell Calcium Oct-Nov;42(4-5):409-17. [PubMed]


Raingo J, Castiglioni AJ, Lipscombe D. (2007) Alternative splicing controls G protein-dependent inhibition of N-type calcium channels in nociceptors.
Nat Neurosci. Mar;10(3):285-92. [PubMed]


Castiglioni AJ, Raingo J, Lipscombe D. (2006) Alternative splicing in the C-terminus of CaV2.2 controls expression and gating of N-type calcium channels.
J Physiol. 1;576(Pt 1):119-34. [PubMed]


Lipscombe D, Raingo J. (2006) Internalizing channels: a mechanism to control pain?
Nat Neurosci. Jan;9(1):8-10. [PubMed]


Helton TD, Xu W, Lipscombe D. (2005) Neuronal L-type calcium channels open quickly and are inhibited slowly.
J Neurosci. 2;25(44):10247-51. [PubMed]


Lipscombe D. (2005) Neuronal proteins custom designed by alternative splicing.
Curr Opin Neurobiol 15(3):358-63. [PubMed]


Lipscombe D, Helton TD, Xu W. (2004) L-type calcium channels: the low down.
J Neurophysiol. 92(5):2633-41. [PubMed]


Lin Y, McDonough SI, Lipscombe D. (2004) Alternative splicing in the voltage-sensing region of N-Type CaV2.2 channels modulates channel kinetics.
J Neurophysiol. 92:2820-2830. [PubMed]


Thaler C, Gray AC, Lipscombe D. (2004) Cumulative inactivation of N-type Cav2.2 calcium channels modified by alternative splicing.
Proceedings of the National Academy of Science, USA. 101:5675-5679. [PubMed]


Bell TJ, Thaler C, Castiglioni AJ, Helton TD, Lipscombe D. (2004) Cell-specific alternative splicing increases calcium channel current density in the pain pathway.
Neuron. 41:127-138. [PubMed]


Lipscombe D, & Castiglioni AJ. (2004) Alternative splicing in voltage-gated calcium channels.
Calcium Channel Pharmacology Kluwer/ Academic/ Plenum Publishing. Ed. Stefan I McDonough. [PubMed]


Lipscombe D, Pan JQ, Gray AC. (2002) Functional diversity in neuronal voltage-gated calcium channels by alternative splicing of Ca(v)alpha1.
Mol Neurobiol. 26(1):21-44. [PubMed]


Lipscombe D. (2002) L-type calcium channels: highs and new lows.
Circ Res. 90(9):933-5. [PubMed]


Xu W, Lipscombe D. (2001) Neuronal Ca(V)1.3alpha(1) L-type channels activate at relatively hyperpolarized membrane potentials and are incompletely inhibited by dihydropyridines.
J Neurosci. 21(16):5944-51. [PubMed]


Lipscombe D. (2001)
"Ion channels", The Encyclopedia of Life Sciences, Macmillan Press.


Pan JQ, Lipscombe D. (2000) Alternative splicing in the cytoplasmic II-III loop of the N-type Ca channel alpha 1B subunit: functional differences are beta subunit-specific.
J Neurosci. 20(13):4769-75. [PubMed]


Schorge S, Gupta S, Lin Z, McEnery MW, Lipscombe D. (1999) Calcium channel activation stabilizes a neuronal calcium channel mRNA.
Nat Neurosci. 2(9):785-90. [PubMed]


Lin Z, Lin Y, Schorge S, Pan JQ, Beierlein M, Lipscombe D. (1999) Alternative splicing of a short cassette exon in alpha1B generates functionally distinct N-type calcium channels in central and peripheral neurons.
J Neurosci. 1;19(13):5322-31. [PubMed]


Lin Z, Haus S, Edgerton J, Lipscombe D. (1997) Identification of functionally distinct isoforms of the N-type Ca2+ channel in rat sympathetic ganglia and brain.
Neuron. 18(1):153-66. [PubMed]


Lin Z, Harris C, Lipscombe D. (1996) The molecular identity of Ca channel alpha 1-subunits expressed in rat sympathetic neurons.
J Mol Neurosci. 7(4):257-67. [PubMed]